Source: http://feedproxy.google.com/~r/RightCelebrity/~3/xtwozHx9duY/
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Tuesday, January 31, 2012
Watch NBC?s Smash Series Premiere (Full Episode)
One week from tonight the NBC show Smash premieres. However I am here to tell you that you don?t have to wait until next Monday to watch it. Nope you can check out the entire episode right here, sweet! I don?t know about you but I can?t wait for the new series Smash to debut and now well I don?t have to. See thanks to my pal Kelsey at NBC I can watch the entire first episode below. You read it correctly the entire thing right here and a whole week early too. In case you aren?t entirely sure what Smash is about, although I am not sure how that can be since the promos for it are literally everywhere but that being said let me give a little run down of the show. The show is a musical drama set on the back drop of a Broadway musical about the infamous Marilyn Monroe. It has a stellar cast that includes the lovely Debra Messing, Oscar Winner Anjelica Huston and American Idol alum Katharine McPhee, to name just a few. Plus the amazing Steven Spielberg is the executive producer so that is pretty cool. Anyway to me it sounds and [...]
Police catch suspect in 75 drug cartel killings (AP)
MONTERREY, Mexico ? Police in northern Mexico have captured an alleged member of the Zetas drug gang who confessed to killing at least 75 people, including many who were pulled off of buses, authorities said Monday.
Enrique Elizondo Flores told investigators 36 of his victims were bus passengers traveling through the town of Cerralvo, near the border with Texas, said Nuevo Leon state security spokesman Jorge Domene.
Elizondo was detained Jan. 20 in the town of Salinas Victoria, but authorities delayed announcing his arrest so they could verify details of his confession, said Nuevo Leon state Attorney General Adrian de la Garza.
Domene said the 35-year-old suspect told investigators he had been working in the area at least three years and that he was in charge of killing members of the rival Gulf drug cartel heading to the towns of Cerralvo and General Trevino. He and other gunmen last January began pulling passengers off of buses as they arrived at Cerralvo's bus station, Domene said.
They are among at least 92 bus passengers that the Zetas are accused of killing in three attacks in January and March 2011. Many the victims were originally from the central state of Guanajuato and had arrived in Cerralvo from the border city of Reynosa, Domene said.
Elizondo distinguished himself "for torturing, maiming and then killing his victims," Domene said.
Last year, authorities in the neighboring state of Tamaulipas unearthed 193 bodies from clandestine graves in the town of San Fernando. Security forces said they were led to the site by members of the Zetas who confessed to kidnapping and killing bus passengers traveling through the area.
The motive for the bus abductions remains unclear. Prosecutors have suggested the gang may be forcefully recruiting people to work for it or trying to kill rivals they suspected were aboard the buses.
Northeast Mexico has been engulfed by a turf battle between the Gulf Cartel and the Zetas since they split in 2010.
More than 47,000 people have been killed nationwide since President Felipe Calderon launched a crackdown against drug traffickers in December 2006.
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Monday, January 30, 2012
Codecademy Becomes A Platform: Now Anyone Can Write Programming Tutorials
One of the most buzzed-about startups over the last few months has been Codecademy ??a site that looks to make programming accessible to just about anyone, with a variety of interactive, web-based courses that have users writing their first lines of code within a few seconds. The site's 'Code Year' program, which invites users to receive one programming lesson each week, racked up a whopping 100,000 signups in only 48 hours ? and it even has the White House?on board. But, as anyone who has spent much time on the site can attest to, Codecademy has had one big problem: there just aren't that many lessons available. And the ones that are on there sometimes seem to be moving too quickly, without many practice exercises to explore and reinforce what you've just learned. Today, the company is launching a feature that will go a long way toward fixing that. Meet the Codecademy Course Creator.Source: http://feedproxy.google.com/~r/Techcrunch/~3/DKsngzBY6V0/
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The man who would defeat Hugo Ch?vez
A young state governor,?Henrique Capriles Radonski is the leading candidate to go up against Venezuela's President Hugo?Ch?vez in elections.
After 12 years orchestrating his Bolivarian Revolution, Venezuelan President Hugo Ch?vez is preparing to run for a fourth, six-year term in power. But a traditionally disjointed opposition has finally begun to work together to battle for his defeat in this year?s Presidential election.
Skip to next paragraphTo say Mr. Ch?vez?s tenure has been eventful would be an understatement. He survived a coup attempt which deposed him for 48 hours, an oil strike that virtually stopped all production for more than two months, and ? he fancifully claimed ? Washington?s attempts to kill him last year by poisoning him with cancer. He also won a victory in overturning term limits, which means he is able to maintain power until defeated at the polls.?
Ch?vez is a formidable foe for the country?s political opposition. His approach to the Venezuelan economy is steeped in oil. He uses profits from the $110 per barrel resource to fund popular social programs, winning deserved favor with the poor. He also owes much of his success to his indelible public relations skills, which resonate with his core support among the poor, and in the early years of his presidency, appealed to the nation?s middle class.?
Are you up on Latin American news? Take our quiz.
Living with 30 percent inflation, regular power outages, and one of the highest murder rates in the world, however, the middle class has since tired of Ch?vez.?A tough fight lies ahead. The candidate who will take on Ch?vez in Venezeula?s October Presidential election will be chosen in primaries held on Feb. 12.
Young state governor Henrique Capriles Radonski is likely to take that mantle. He's less known outside the country than his former rival,?Leopoldo L?pez, who has spoken out against Ch?vez on the world stage. Mr. L?pez?was set to be the opposition?s frontrunner until the government disqualified him from holding office under a law that many critics say was simply created to stifle those with a chance at challenging the president. Despite that, L?pez was still high in the polls until a couple of weeks ago (Jan. 24) when he stepped out of the race, redirecting his considerable momentum to Mr. Capriles? campaign. With the?support of L?pez, Capriles is expected to win the February primary.
Unlike L?pez and other opposition candidates who are seen as wealthy outsiders by the country?s poor, Capriles has been courting the barrios of Venezuela rather than the boardrooms of the United States, appealing to Ch?vez?s core support.
?He?s the only one who can penetrate the poor,? says Carlos Romero, a political analyst at the Central University of Venezuela.
Source: http://rss.csmonitor.com/~r/feeds/csm/~3/FlvX1KEfaJc/The-man-who-would-defeat-Hugo-Chavez
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Sunday, January 29, 2012
That which does not kill yeast makes it stronger
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Public release date: 29-Jan-2012[ | E-mail |
Share ] Contact: Gina Kirchweger
gxk@stowers.org
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Stowers Institute for Medical Research
Stress-induced genomic instability facilitates rapid cellular adaption in yeast
KANSAS CITY, MO Cells trying to keep pace with constantly changing environmental conditions need to strike a fine balance between maintaining their genomic integrity and allowing enough genetic flexibility to adapt to inhospitable conditions. In their latest study, researchers at the Stowers Institute for Medical Research were able to show that under stressful conditions yeast genomes become unstable, readily acquiring or losing whole chromosomes to enable rapid adaption.
The research, published in the January 29, 2012, advance online issue of Nature, demonstrates that stress itself can increase the pace of evolution by increasing the rate of chromosomal instability or aneuploidy. The observation of stress-induced chromosome instability casts the molecular mechanisms driving cellular evolution into a new perspective and may help explain how cancer cells elude the body's natural defense mechanisms or the toxic effects of chemotherapy drugs.
"Cells employ intricate control mechanisms to maintain genomic stability and prevent abnormal chromosome numbers," says the study's leader, Stowers investigator Rong Li, Ph.D. "We found that under stress cellular mechanisms ensuring chromosome transmission fidelity are relaxed to allow the emergence of progeny cells with diverse aneuploid chromosome numbers, producing a population with large genetic variation."
Known as adaptive genetic change, the concept of stress-induced genetic variation first emerged in bacteria and departs from a long-held basic tenet of evolutionary theory, which holds that genetic diversityevolution's raw material from which natural selection picks the best choice under any given circumstancearises independently of hostile environmental conditions.
"From an evolutionary standpoint it is a very interesting finding," says graduate student and first author Guangbo Chen. "It shows how stress itself can help cells adapt to stress by inducing chromosomal instability."
Aneuploidy is most often associated with cancer and developmental defects and has recently been shown to reduce cellular fitness. Yet, an abnormal number of chromosomes is not necessarily a bad thing. Many wild yeast strains and their commercial cousins used to make bread or brew beer have adapted to their living environs by rejiggering the number of chromosomes they carry. "Euploid cells are optimized to thrive under 'normal' conditions," says Li. "In stressful environments aneuploid cells can quickly gain the upper hand when it comes to finding creative solutions to roadblocks they encounter in their environment."
After Li and her team had shown in an earlier Nature study that aneuploidy can confer a growth advantage on cells when they are exposed to many different types of stress conditions, the Stowers researchers wondered whether stress itself could increase the chromosome segregation error rate.
To find out, Chen exposed yeast cells to different chemicals that induce various types of general stress and assessed the loss of an artificial chromosome. This initial screen revealed that many stress conditions, including oxidative stress, increased the rate of chromosome loss ten to 20-fold, a rate typically observed when cells are treated with benomyl, a microtubule inhibitor that directly affects chromosome segregation.
The real surprise was radicicol, a drug that induces proteotoxic stress by inhibiting a chaperone protein, recalls Chen. "Even at a concentration that barely slows down growth, radicicol induced extremely high levels of chromosome instability within a very short period of time," he says.
Continued growth of yeast cells in the presence of radicicol led to the emergence of drug-resistant colonies that had acquired an additional copy of chromosome XV. Yeast cells pretreated briefly with radicicol to induce genomic instability also adapted more efficiently to the presence of other drugs including fluconazole, tunicamycin, or benomyl, when compared to euploid cells.
Interestingly, certain chromosome combinations dominated in colonies that were resistant to a specific drug. Fluconazole-resistant colonies typically gained an extra copy of chromosome VIII, tunicamycin-resistant colonies tended to lose chromosome XVI, while a majority of benomyl-resistant colonies got rid of chromosome XII. "This suggested to us that specific karyotypes are associated with resistance to certain drugs," says Chen.
Digging deeper, Chen grew tunicamycin-resistant yeast cells, which had adapted to the presence of the antibiotic by losing one copy of chromosome XVI, under drug-free conditions. Before long, colonies of two distinct sizes emerged. He quickly discovered that the faster growing colonies had regained the missing chromosome. By returning to a normal chromosome XVI number, these newly arisen euploid cells had acquired a distinctive growth advantage over their aneuploid neighbors. But most importantly, the fast growing yeast cells were no longer resistant to tunicamycin and thus clearly linking tunicamycin resistance to the loss of chromosome XVI.
###
Researchers who also contributed to the work include William D. Bradford and Chris W. Seidel both at the Stowers Institute for Medical Research.
The study was funded in part by the National Institute of General Medical Sciences.
About the Stowers Institute for Medical Research
The Stowers Institute for Medical Research is a non-profit, basic biomedical research organization dedicated to improving human health by studying the fundamental processes of life. Jim Stowers, founder of American Century Investments, and his wife Virginia opened the Institute in 2000. Since then, the Institute has spent over 800 million dollars in pursuit of its mission.
Currently the Institute is home to over 500 researchers and support personnel; over 20 independent research programs; and more than a dozen technology development and core facilities. Learn more about the Institute at www.stowers.org.
[ | E-mail | Share ] ?
AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
Public release date: 29-Jan-2012[ | E-mail |
Share ] Contact: Gina Kirchweger
gxk@stowers.org
816-806-1036
Stowers Institute for Medical Research
Stress-induced genomic instability facilitates rapid cellular adaption in yeast
KANSAS CITY, MO Cells trying to keep pace with constantly changing environmental conditions need to strike a fine balance between maintaining their genomic integrity and allowing enough genetic flexibility to adapt to inhospitable conditions. In their latest study, researchers at the Stowers Institute for Medical Research were able to show that under stressful conditions yeast genomes become unstable, readily acquiring or losing whole chromosomes to enable rapid adaption.
The research, published in the January 29, 2012, advance online issue of Nature, demonstrates that stress itself can increase the pace of evolution by increasing the rate of chromosomal instability or aneuploidy. The observation of stress-induced chromosome instability casts the molecular mechanisms driving cellular evolution into a new perspective and may help explain how cancer cells elude the body's natural defense mechanisms or the toxic effects of chemotherapy drugs.
"Cells employ intricate control mechanisms to maintain genomic stability and prevent abnormal chromosome numbers," says the study's leader, Stowers investigator Rong Li, Ph.D. "We found that under stress cellular mechanisms ensuring chromosome transmission fidelity are relaxed to allow the emergence of progeny cells with diverse aneuploid chromosome numbers, producing a population with large genetic variation."
Known as adaptive genetic change, the concept of stress-induced genetic variation first emerged in bacteria and departs from a long-held basic tenet of evolutionary theory, which holds that genetic diversityevolution's raw material from which natural selection picks the best choice under any given circumstancearises independently of hostile environmental conditions.
"From an evolutionary standpoint it is a very interesting finding," says graduate student and first author Guangbo Chen. "It shows how stress itself can help cells adapt to stress by inducing chromosomal instability."
Aneuploidy is most often associated with cancer and developmental defects and has recently been shown to reduce cellular fitness. Yet, an abnormal number of chromosomes is not necessarily a bad thing. Many wild yeast strains and their commercial cousins used to make bread or brew beer have adapted to their living environs by rejiggering the number of chromosomes they carry. "Euploid cells are optimized to thrive under 'normal' conditions," says Li. "In stressful environments aneuploid cells can quickly gain the upper hand when it comes to finding creative solutions to roadblocks they encounter in their environment."
After Li and her team had shown in an earlier Nature study that aneuploidy can confer a growth advantage on cells when they are exposed to many different types of stress conditions, the Stowers researchers wondered whether stress itself could increase the chromosome segregation error rate.
To find out, Chen exposed yeast cells to different chemicals that induce various types of general stress and assessed the loss of an artificial chromosome. This initial screen revealed that many stress conditions, including oxidative stress, increased the rate of chromosome loss ten to 20-fold, a rate typically observed when cells are treated with benomyl, a microtubule inhibitor that directly affects chromosome segregation.
The real surprise was radicicol, a drug that induces proteotoxic stress by inhibiting a chaperone protein, recalls Chen. "Even at a concentration that barely slows down growth, radicicol induced extremely high levels of chromosome instability within a very short period of time," he says.
Continued growth of yeast cells in the presence of radicicol led to the emergence of drug-resistant colonies that had acquired an additional copy of chromosome XV. Yeast cells pretreated briefly with radicicol to induce genomic instability also adapted more efficiently to the presence of other drugs including fluconazole, tunicamycin, or benomyl, when compared to euploid cells.
Interestingly, certain chromosome combinations dominated in colonies that were resistant to a specific drug. Fluconazole-resistant colonies typically gained an extra copy of chromosome VIII, tunicamycin-resistant colonies tended to lose chromosome XVI, while a majority of benomyl-resistant colonies got rid of chromosome XII. "This suggested to us that specific karyotypes are associated with resistance to certain drugs," says Chen.
Digging deeper, Chen grew tunicamycin-resistant yeast cells, which had adapted to the presence of the antibiotic by losing one copy of chromosome XVI, under drug-free conditions. Before long, colonies of two distinct sizes emerged. He quickly discovered that the faster growing colonies had regained the missing chromosome. By returning to a normal chromosome XVI number, these newly arisen euploid cells had acquired a distinctive growth advantage over their aneuploid neighbors. But most importantly, the fast growing yeast cells were no longer resistant to tunicamycin and thus clearly linking tunicamycin resistance to the loss of chromosome XVI.
###
Researchers who also contributed to the work include William D. Bradford and Chris W. Seidel both at the Stowers Institute for Medical Research.
The study was funded in part by the National Institute of General Medical Sciences.
About the Stowers Institute for Medical Research
The Stowers Institute for Medical Research is a non-profit, basic biomedical research organization dedicated to improving human health by studying the fundamental processes of life. Jim Stowers, founder of American Century Investments, and his wife Virginia opened the Institute in 2000. Since then, the Institute has spent over 800 million dollars in pursuit of its mission.
Currently the Institute is home to over 500 researchers and support personnel; over 20 independent research programs; and more than a dozen technology development and core facilities. Learn more about the Institute at www.stowers.org.
[ | E-mail | Share ] ?
AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
Source: http://www.eurekalert.org/pub_releases/2012-01/sifm-twd012512.php
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Saturday, January 28, 2012
Tech stocks: Growth ahead for handheld game consoles
Tech stocks subsector face growing competition from mobile phones and tablets. But one tech stocks analysts sees up to 20 percent revenue growth in 2012 for makers of handheld game consoles.?
The market for handheld devices may be getting squeezed by competition from mobile gaming platforms like smartphones and tablet PCs, but research firm International Data Corporation (IDC) is predicting further growth for the sector and expects revenues to jump as much as 20 percent this year, after single-digit percentage growth in 2011.
Skip to next paragraphAccording to IDC's research manager for gaming Lewis Ward, the experience that comes from playing handheld devices is unique to users, and adds that the short battery lifespan in mobile gaming devices will always give its handheld console rivals an edge.
?"I think the stereoscopic 3D effect [in handheld devices] is quite compelling in many respects," Ward told CNBC on Thursday. ?Obviously Nintendo has some extraordinary IP, Pokemon, and many other titles which are unique to the platform and therefore provides an experience you simply can't get somewhere else.?
??One of the important drivers for adult gamers in particular is the ability to save your battery life on your cellphone and therefore make a dedicated handheld that much more attractive,? he added.
?A recent report from IDC projects the share of video gaming revenue for handheld console devices and their related software will fall to 59 percent in 2015, compared to the current 66 percent, as more users shift to the mobile gaming platform. Even so, Ward is predicting growth for the sector.
?"I'm anticipating growth in dedicated handhelds and console gaming in 2012," Ward said. "The market has been going sideways in many respects for the past couple of years, but I'm expecting some respectable results in the fourth quarter from major providers."?
?Tech heavyweight?Microsoft?beat analyst expectations in its fourth quarter earnings last week, helped by strong sales of its Xbox consoles.?Sony, which reports next week, is expected to barely break even in the lucrative October-December quarter, although Ward expects its handheld gaming unit do well this year when its latest PlayStation Vita console rolls out in the American and European markets in February.
Gaming giant?Nintendo, meanwhile,?forecasts a $580 million operating loss for the full year to March 31, after posting a 61 percent drop in third quarter operating profit?on Thursday. The company also cut its forecast for its latest 3DS handheld console to 14 million units from 16 million after poor sales.
?While investors have questioned the outlook for Nintendo on reports its chief gaming architect Shigeru Miyamoto is stepping down, Ward says the concerns are overblown.
??My understanding is that there's been a lot of grooming going on over the years and there's a lot of very talented people within Nintendo and I fully expect that the legacy will continue. I believe its in good hands in many respects,? he noted.
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Genetic screens bring new hope for tackling sleeping sickness
Thursday, January 26, 2012
Research led by scientists at the London School of Hygiene & Tropical Medicine has exploited a revolutionary genetic technique to discover how human African Trypanosomiasis (HAT) drugs target the parasite which causes the disease. The new knowledge could help lead to the development of better treatments for the tens of thousands of people in sub-Saharan Africa who are affected each year.
The findings, published in Nature, are based on the simultaneous analysis of thousands of genes and the action of the five drugs effective against HAT, also known as sleeping sickness. The research was a collaboration between LSHTM, the Wellcome Trust Sanger Institute and the University of Cambridge and was funded by the Wellcome Trust.
The disease ? usually fatal if left untreated - is caused by a parasite called Trypanosoma brucei, which is transmitted by the tsetse fly and attacks the central nervous system. Although treatment is available, until now there has been little understanding of how and why the drugs are particularly effective against African trypanosomes and therefore limited scope to tackle resistance when it arises. In particular, an arsenic-based drug called melarsoprol is increasingly ineffective and has the added problem of severe toxicity in patients; it is only because HAT is such a lethal disease that this drug is still in use.
Employing a process of specific gene disruption that prevents the parasite from producing its signature proteins, and targeting one gene in each cell (the parasite is unicellular), the scientists identified which modifications resulted in drug resistance. This implied that the original gene was essential for the drug to work. The technique, called RNA interference target sequencing (RIT-seq), depends upon technology developed by scientists at LSHTM over several years and a high-throughput DNA sequencing approach developed in collaboration with researchers at the Wellcome Trust Sanger Institute.
The team screened the entire T. brucei genome of 7,500 genes and found a total of 50 genes, and therefore 50 proteins, that are linked to drug action and resistance. With this information, the group analysed the biological processes those proteins are involved in and deduced how the drugs interact with the parasite.
Lead researcher Dr David Horn, Reader in Molecular Biology at LSHTM, said: "We now know a lot more about how these drugs work. This new understanding of how these medications kill parasites, or fail to kill parasites, could lead to the development of tests that guide the intervention strategy as well as more active and safer intervention options. What is important now is to begin the process of translating the new findings into clinical advances such as new diagnostics and therapies."
###
London School of Hygiene & Tropical Medicine: http://www.lshtm.ac.uk
Thanks to London School of Hygiene & Tropical Medicine for this article.
This press release was posted to serve as a topic for discussion. Please comment below. We try our best to only post press releases that are associated with peer reviewed scientific literature. Critical discussions of the research are appreciated. If you need help finding a link to the original article, please contact us on twitter or via e-mail.
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Source: http://www.labspaces.net/117070/Genetic_screens_bring_new_hope_for_tackling_sleeping_sickness
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Friday, January 27, 2012
The nations weather (AP)
Weather Underground Forecast for Friday, January 27, 2012.
Wet weather will persist across the Eastern US, while snow showers move through the Rockies on Friday. A strong low pressure system over the Eastern Valleys continues moving northward, over the Northeastern US and into eastern Canada. Flow around this system pushes a warm front over the Northeast, kicking up scattered rain showers. Rainfall totals along this front will range from 1.0 to 1.5 inches. Expect cooler temperatures north of this front to produce freezing rain and snow showers over the far Northeast. Additionally, moisture will wrap around this system to the west, kicking up scattered snow showers across the Great Lakes. Snowfall accumulation in these areas will range from 1 to 3 inches. To the South, a cold front will extend south of this system and continue sweeping across the Southeastern states. Some areas may see some severe thunderstorms with heavy rainfall and strong winds. Rainfall totals in most areas will range from 1 to 2 inches, with more likely in areas of severe thunderstorm development. By Friday evening, this system will move offshore and into the Atlantic Ocean. This will bring an end to scattered showers and thunderstorms across the Southeast.
Out West, a low pressure system and associated cold front continue advancing eastward through the Rockies. Some residual moisture with this system will bring periods of heavy snow to the Northern and Central Rockies. Expect snowfall accumulation to range from 6 to 12 inches across Colorado, while Montana and Wyoming will see 6 to 10 inches of new snow. The leading edge of this system will quickly move into the Northern Plains and Upper Midwest. Expect 1 to 3 inches of new snow in these areas. Temperatures in the Lower 48 states Thursday have ranged from a morning low of -3 degrees at Clayton Lake, Maine to a high of 85 degrees at Orlando, Fla.
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Potty-room pilfering: Auto flushers stolen in Ohio
COLUMBUS, Ohio (AP) ? A restroom rip-off in central Ohio has automatic flushers disappearing from the bathrooms at restaurants and other businesses.
Police say it's been happening in at least a couple Columbus suburbs. Investigators don't know if the thefts are related.
Handyman John Hahn tells WBNS-TV (http://bit.ly/yGqJ3c ) the flushers are likely being stolen for scrap because they contain a metal called red brass that can bring $2.50 per pound.
He says safeguards are needed because the flushers can be costly to repair.
___
Information from: WBNS-TV, http://www.10tv.com/
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Thursday, January 26, 2012
Helmet catch will forever define Tyree's career
EAST RUTHERFORD, N.J. (AP) ? Eli Manning took home the MVP. Plaxico Burress had the game-winning catch. David Tyree got the biggest prize in the 2008 Super Bowl ? an unforgettable moment that forever will be his.
No play in the New York Giants' 17-14 victory over the New England Patriots has been shown more than Tyree's fourth-quarter catch of a ball against his helmet with defender Rodney Harrison draped over him.
It led to Manning's last-minute touchdown pass to Burress and changed Tyree's life.
The New Jersey native became a hero in the New York metropolitan area, earned up to $15,000 per appearance fees, made numerous television and radio appearances and wrote a book.
"The truth of it was I was never going to have a moment ever in my career that was going to eclipse that," Tyree said in a conference call about what is known as "The Catch" in Giants history. "It gave me a sense of peace as far as moving on and knowing I had a career that I can be satisfied with.
"It's not about the money; it's about, for me, having a moment that transcends my own personal career, to be a part of Giants history, NFL history, Super Bowl history," Tyree said. "That's something that most people who've had far better careers than myself never had."
A sixth-round draft pick out of Syracuse by the Giants in 2003, Tyree didn't do much after the Super Bowl. He hurt his knee and missed the following season, and spent his last year with Baltimore, failing to make a catch. He retired in 2010 after signing a one-day contract with the Giants.
Off the field, Tyree has turned around his life. His days of drinking alcohol and smoking marijuana are long behind him and he has become born-again Christian
The 32-year-old father of six serves as the director of strategic partnerships at Tepidus Group, a company involved in wealth management, marketing and philanthropic ventures. He is also writing another book with his wife, Leilah, that intends to "challenge the core of our culture."
One thing they will address, he said is "how we esteem people who are in the limelight and have been given pedestals and platforms."
Tyree also is the senior vice president of the International Children's Support Foundation, which tries to improve the lives children.
The Pro Bowl special teams player also isn't afraid to express his religious beliefs. He has come out against same sex marriages, and he has been criticized by many.
"I knew what I was getting myself into," he said.
Tyree plans to attend the Super Bowl next week and he said he might get a few speaking engagements out of it.
Tyree has watched the Giants (12-7) current run to a Super Bowl rematch with the Patriots and he marvels at the similarities, calling them spooky.
New York has once again made a late-season rush and done its most damage in the postseason on the road, knocking off the defending champion Green Bay Packers in the NFC division round and the San Francisco 49ers in the conference title game.
After the 2007 regular season, the Giants won all their playoff games on the road, winning at Tampa, Dallas and Green Bay.
Placekicker Lawrence Tynes made game-winning field goals in overtime both conference championship games.
"I might have been just as speechless as I was when we won the Super Bowl four years ago," Tyree said.
Tyree had three catches in the Super Bowl, including one for a touchdown. The one everybody remembers is the 32-yarder on a third-and-5 play with 1:15 to play and the Giants trailing the then-unbeaten Patriots 14-10.
Manning avoided a big pass rush and lofted a long pass down the middle. Tyree leapt, got his hands on the ball, then pinned it against his helmet, first with one hand and then the other. All the while, Harrison was pulling Tyree to the ground by the arm.
Harrison said Wednesday that the only time he thought about the play was when his son gave him a book for Christmas a couple of years ago with a picture of the play on the front cover.
"It's in my office," Harrison said. "Every time I walk in my office I see it so I'm reminded of it every single day.
"But it doesn't haunt me. It's something that happened, you know. It's almost funny because I look back at my career and I started thinking, do I have any regrets? And I don't really have any regrets because I played hard, I played tough, I played physical and you ask this guy to make this catch a million other times, he doesn't make it. So it's just one of those things that you look at and say, 'wow, you know what? No matter what I could have done, he was going to catch that ball. It was just meant to happen.' "
Call it fate. But it's a catch that made Tyree famous and gave him a place in football history.
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Wednesday, January 25, 2012
Scientists create first atomic X-ray laser
ScienceDaily (Jan. 25, 2012) ? Scientists working at the U.S. Department of Energy's (DOE) SLAC National Accelerator Laboratory have created the shortest, purest X-ray laser pulses ever achieved, fulfilling a 45-year-old prediction and opening the door to a new range of scientific discovery.
The researchers, reporting in Nature, aimed SLAC's Linac Coherent Light Source (LCLS) at a capsule of neon gas, setting off an avalanche of X-ray emissions to create the world's first "atomic X-ray laser."
"X-rays give us a penetrating view into the world of atoms and molecules," said physicist Nina Rohringer, who led the research. A group leader at the Max Planck Society's Advanced Study Group in Hamburg, Germany, Rohringer collaborated with researchers from SLAC, DOE's Lawrence Livermore National Laboratory and Colorado State University.
"We envision researchers using this new type of laser for all sorts of interesting things, such as teasing out the details of chemical reactions or watching biological molecules at work," she added. "The shorter the pulses, the faster the changes we can capture. And the purer the light, the sharper the details we can see."
The new atomic X-ray laser fulfills a 1967 prediction that X-ray lasers could be made in the same manner as many visible-light lasers -- by inducing electrons to fall from higher to lower energy levels within atoms, releasing a single color of light in the process. But until 2009, when LCLS turned on, no X-ray source was powerful enough to create this type of laser.
To make the atom laser, LCLS's powerful X-ray pulses -- each a billion times brighter than any available before -- knocked electrons out of the inner shells of many of the neon atoms in the capsule. When other electrons fell in to fill the holes, about one in 50 atoms responded by emitting a photon in the X-ray range, which has a very short wavelength. Those X-rays then stimulated neighboring neon atoms to emit more X-rays, creating a domino effect that amplified the laser light 200 million times.
Although LCLS and the neon capsule are both lasers, they create light in different ways and emit light with different attributes. The LCLS passes high-energy electrons through alternating magnetic fields to trigger production of X-rays; its X-ray pulses are brighter and much more powerful. The atomic laser's pulses are only one-eighth as long and their color is much more pure, qualities that will enable it to illuminate and distinguish details of ultrafast reactions that had been impossible to see before.
"This achievement opens the door for a new realm of X-ray capabilities," said John Bozek, LCLS instrument scientist. "Scientists will surely want new facilities to take advantage of this new type of laser."
For example, researchers envision using both LCLS and atomic laser pulses in a synchronized one-two punch: The first laser triggers a change in a sample under study, and the second records with atomic-scale precision any changes that occurred within a few quadrillionths of a second.
In future experiments, Rohringer says she will try to create even shorter-pulsed, higher-energy atomic X-ray lasers using oxygen, nitrogen or sulfur gas.
Additional authors included Richard London, Felicie Albert, James Dunn, Randal Hill and Stefan P. Hau-Riege from Lawrence Livermore National Laboratory (LLNL); Duncan Ryan, Michael Purvis and Jorge J. Rocca from Colorado State University; and Christoph Bostedt from SLAC.
The work was supported by Lawrence Livermore National Laboratory's Laboratory Directed Research and Development Program. Authors Roca, Purvis and Ryan were supported by the DOE Office of Science. LCLS is a national scientific user facility operated by SLAC and supported by DOE's Office of Science.
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The above story is reprinted from materials provided by DOE/SLAC National Accelerator Laboratory.
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Journal Reference:
- Nina Rohringer, Duncan Ryan, Richard A. London, Michael Purvis, Felicie Albert, James Dunn, John D. Bozek, Christoph Bostedt, Alexander Graf, Randal Hill, Stefan P. Hau-Riege, Jorge J. Rocca. Atomic inner-shell X-ray laser at 1.46 nanometres pumped by an X-ray free-electron laser. Nature, 2012; 481 (7382): 488 DOI: 10.1038/nature10721
Note: If no author is given, the source is cited instead.
Disclaimer: Views expressed in this article do not necessarily reflect those of ScienceDaily or its staff.
Source: http://feeds.sciencedaily.com/~r/sciencedaily/~3/L8DKDJB3JwE/120125132819.htm
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Theatrhythm Final Fantasy box points to first paid DLC for Nintendo 3DS
3DS owners have been waiting (and waiting) for a chance to take advantage of a downloadable content market, and while Nintendo already accomplished the tough part (read: launching it) a few days back, there's still been no word on when paid content would make an appearance. Pushing those freebies aside is Theatrhythm Final Fantasy, which is seemingly destined to be the first 3DS title in existence to offer up enhancements in exchange for a few yen. The box here is actually an "early retail dummy unit," though the verbiage on the back makes quite clear that downloadable material will be available at a cost. Furthermore, there's a heretofore unseen Nintendo Network badge on the front, which may be a new look for the existing Nintendo Wi-Fi Connection. At any rate, the game is scheduled to ship on February 16th in Japan, after which all of this will-it-won't-it drama will presumably be cleared up.Theatrhythm Final Fantasy box points to first paid DLC for Nintendo 3DS originally appeared on Engadget on Sun, 22 Jan 2012 23:54:00 EDT. Please see our terms for use of feeds.
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Tuesday, January 24, 2012
Kim Kardashian Donates $50,000 to The Trevor Project (omg!)
Kim Kardashian is giving back.
The Kourtney and Kim Take New York reality star recently donated the $50,000 she raised during a September 2011 fundraiser to The Trevor Project, an organization that provides suicide prevention services to LGBT teens.
PHOTOS: A-list LGBT allies
Kardashian, 31, raised the funds during a trip to the Cantor Fitzgerald offices in New York City, where she was put to work on the trading floor.
PHOTOS: Kim and sister Kourtney explore New York City
"The firm lost more than 600 employees in the 9/11 attacks on the World Trade Center in 2001 and on the 10th anniversary of the attacks, they donated all revenues from their trades to charities around the world," she wrote on her blog at the time. "I was honored to take part!"
PHOTOS: Celebrities' good deeds
Kardashian joins celebrities including Glee's Kevin McHale, Daniel Radcliffe, Adam Lambert and Kathy Griffin in supporting The Trevor Project, which aims to end suicide among lesbian, gay, bisexual, transgender and questioning young people.
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Seal and Heidi Klum Have Announced Their Divorce
Seal and Heidi Klum have announced that their storybook marriage is coming to the end of the runway. In a statement Sunday night, the power couple announced their separation after rumors swirled over the weekend that a divorce was imminent. “While we have enjoyed seven very loving, loyal and happy years of marriage, after much [...]
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Monday, January 23, 2012
MS judge to hear AG's challenge of Barbour pardons (AP)
JACKSON, Miss. ? The Mississippi attorney general's office says it has not been able to find a convicted killer pardoned by Haley Barbour during his final days as governor.
Hinds County Circuit Judge Tomie Green ordered five former inmates who worked as Governor's Mansion trusties and were pardoned by Barbour to appear in court Monday, but authorities haven't located Joseph Ozment. He was convicted in 1994 of killing a man during a robbery.
Green scheduled a 3 p.m. CST hearing to consider arguments from Attorney General Jim Hood, who's challenging some of Barbour's 198 end-of-term pardons.
Hood wants to return recently freed inmates to prison. Most of those who could lose pardons were out of prison before Barbour's action.
Republican Barbour has accused Hood, a Democrat, of partisan politics.
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Beijing releases key air pollution data
FILE - In this Tuesday, Jan. 10, 2012 file photo, a man rides an electric bike crossing a street shrouded by haze in Beijing, China. Caving to public pressure, Beijing environmental authorities started releasing more detailed air quality data Saturday, Jan. 21, 2012, that may better reflect how bad the Chinese capital's air pollution is. (AP Photo/Andy Wong, File)
FILE - In this Tuesday, Jan. 10, 2012 file photo, a man rides an electric bike crossing a street shrouded by haze in Beijing, China. Caving to public pressure, Beijing environmental authorities started releasing more detailed air quality data Saturday, Jan. 21, 2012, that may better reflect how bad the Chinese capital's air pollution is. (AP Photo/Andy Wong, File)
BEIJING (AP) ? Caving to public pressure, Beijing environmental authorities started releasing more detailed air quality data Saturday that may better reflect how bad the Chinese capital's air pollution is.
The initial measurements were low on a day where you could see blue sky. After a week of smothering smog, the skies over the city were being cleared by a north wind.
The readings of PM2.5 ? particulate matter less than 2.5 micrometers in size or about 1/30th the average width of a human hair ? were being posted on Beijing's environmental monitoring center's website. Such small particulates can penetrate deep into the lungs, so measuring them is considered a more accurate reflection of air quality than other methods.
It is the first time Beijing has publicly revealed PM2.5 data and follows a clamor of calls by citizens on social networking sites tired of breathing in gray and yellow air. The U.S. Embassy measures PM2.5 from a device on its rooftop and releases the results, and some residents have even tested the air around their neighborhoods and posted the results online.
Beijing is releasing hourly readings of PM2.5 that are taken from one monitoring site about 4 miles (7 kilometers) west of Tiananmen Square, the monitoring center's website said Saturday. It said the data was for research purposes and the public should only use it as a reference.
The reading at noon Saturday was 0.015 mg/m3, which would be classed as "good" for a 24-hour exposure at that level, according to U.S. Environmental Protection Agency standards. The U.S. Embassy reading taken from its site on the eastern edge of downtown Beijing said its noon reading was "moderate." Its readings are posted on Twitter.
Steven Andrews, an environmental consultant who has studied Beijing's pollution data since 2006, said he was "already a bit suspicious" of Beijing's PM2.5 data. Within the 24-hour period to noon Saturday, Beijing reported seven hourly figures "at the very low level" of 0.003 milligrams per cubic meter.
"In all of 2010 and 2011, the U.S. Embassy reported values at or below that level only 18 times out of over 15,000 hourly values or about 0.1 percent of the time," said Andrews. "PM2.5 concentrations vary by area so a direct comparison between sites isn't possible, but the numbers being reported during some hours seem surpisingly low."
The Beijing center had promised to release PM2.5 data by the start of the Chinese Lunar New Year on Monday. It has six sites that can test for PM2.5 and 27 that can test for the larger, coarser PM10 particles that are considered less hazardous. The center is expected to buy equipment and build more monitoring sites to enable PM2.5 testing.
Beijing wasn't expected to include PM2.5 in its daily roundups of the air quality anytime soon. Those disclosures, for example "light" or "serious," are based on the amount of PM10, sulfur dioxide and nitrogen dioxide in the air.
Beijing interprets air quality using less stringent standards than the U.S. Embassy, so often when the government says pollution is "light," the embassy terms it "hazardous."
"There has been tremendous amounts of attention in the Chinese media ? whichever newspaper you pick up, whichever radio station you listen to, channel you watch ? they are all talking about PM2.5 and how levels are so high," said Andrews.
"What has been so powerful is that people are skeptical, and I think rightly skeptical," about the government's descriptions of data, he said.
___
Online:
Beijing center's readings (in Chinese): http://zx.bjmemc.com.cn/
The U.S. Embassy's Twitter feed: https://twitter.com/beijingair
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Sunday, January 22, 2012
Major powers divided on approach to Iran (Reuters)
WASHINGTON (Reuters) ? Major powers are divided over what to put on the table should Iran resume talks on curbing its nuclear program and whether to allow it to continue enriching uranium to some degree, diplomats said on Friday.
Britain, China, France, Germany, Russia and the United States on Friday signaled their openness to fresh talks about Iran's nuclear program, which the West suspects is a cover to develop an atomic bomb but Iran says is to generate electricity.
EU foreign policy chief Catherine Ashton, who represents the group, issued a statement making clear that a diplomatic path remains open to Iran despite tougher sanctions and fresh speculation of a military strike on its nuclear facilities.
"The EU3+3 has always been clear about the validity of the dual track approach," Ashton's spokesperson said in a statement that also formally released her October 21 letter offering to resume talks with Iran. "We are waiting for the Iranian reaction."
The dual track refers to the combination of sanctions and diplomacy to try to curtail Iran's nuclear programs.
The release of the statement and the letter itself appeared be an effort to demonstrate that the major powers are willing to talk to Iran, while reiterating their demands that Tehran must return to the table willing to talk about its nuclear program.
It also appeared to reflect frustration at recent Iranian statements hinting at a willingness to return to the table but Tehran's failure to formally respond to the letter and commit to discussing the nuclear program in earnest.
NEGOTIATING STRATEGY UNCLEAR
If the Iranians were willing to resume talks, it is not clear what negotiating strategy the six major powers, which are known in diplomatic parlance both as the P5+1 and as the EU3+3 - might employ, notably on any "confidence-building measures."
"There is no agreement inside the P5+1 on how such confidence-building measures should or should not be presented to the Iranians," said one diplomat.
A central issue is whether the group might ask Iran to cease enriching uranium to the higher level of 20 percent but allow it, at least for a time, to continue enriching at lower levels - a stance partly at odds with the group's past positions.
Uranium enrichment is a process that at low levels can yield fuel for nuclear power plants or, if carried out to much higher levels of purity, can generate fissile material for bombs.
Multiple U.N. Security Council resolutions have called on Iran to suspend its uranium enrichment and related activities, and the P5+1 group has taken the view that it must suspend such activities during any serious negotiation.
To permit Iran, even for a period, to enrich at lower levels would be something of a concession by world powers, although they have previously offered a temporary "freeze-for-freeze" in which Iran would halt expansion of its nuclear program and the major powers would not pursue additional sanctions.
Diplomats said the United States favored the idea while others were more skeptical.
Asked why some members of the group might be willing to let Iran continue to enrich at lower levels, at least for a period, one diplomat said it reflected a desire to give diplomacy every possible chance to succeed.
"That really is the crux of it. You want to be able to say that you pursued every option diplomatically to try to get Iran to halt its program," he said.
NO "BACKSLIDING"
Daryl Kimball of the Washington-based Arms Control Association said he understood that the United States and others in the group were prepared to propose a halt to enrichment at the 20-percent level and, probably, the removal of some or all of the stock of such material that Iran has already produced.
In exchange, the P5+1 would provide fuel for the Tehran Research Reactor, essentially updating a proposal it put forward in October 2009, before Iran was known to have begun enriching to the 20-percent level.
"This proposal is being presented as an additional confidence-building step," Kimball said. "It does not represent backsliding."
A diplomat said that proponents of the idea would argue that the nations negotiations with Iran had not softened their terms and that Iran must still suspend all its enrichment-related activities during any serious negotiation.
"It's just an issue of sequencing," he said, reflecting the view of advocates. The counter-argument, he said, was that the Iranians might simply "pocket" such a proposal as a concession allowing them to continue enriching.
Diplomats have long said it made no sense to allow Iran to continue its suspect nuclear activities during talks because Tehran could stall the negotiations while perfecting its technology and advancing toward nuclear capability.
A senior Obama administration official told Reuters that if talks were to resume, the group would have a common stance.
"If the Iranians accept the offer of the P5+1 to have talks on the basis of High Representative Ashton's October letter, we fully expect a unified P5+1 approach to the talks," the official said.
(Reporting by Arshad Mohammed; Editing by Ross Colvin and Xavier Briand)
Source: http://us.rd.yahoo.com/dailynews/rss/iran/*http%3A//news.yahoo.com/s/nm/20120121/wl_nm/us_iran
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Video: Talking Numbers: How to Trade Tech
Charting the outlook for Texas Instruments and the tech sector, with Abigail Doolittle, Peak Theories, and Peter Boockvar, Miller Tabak.
Related Links:
Business & financial news headlines from msnbc.com
Source: http://video.msnbc.msn.com/cnbc/46075615/
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Saturday, January 21, 2012
Former Army soldier sentenced for killing wife, baby (Reuters)
ANCHORAGE (Reuters) ? A former Army soldier who was convicted of killing his wife and baby daughter shortly after returning from combat in Afghanistan was sentenced on Friday to 80 years in prison for the crimes.
Kip Lynch, 22, was found guilty last summer of first degree murder in the April 2010 shooting death of his 19-year-old wife Racquell and second-degree murder of their 8-month old baby, Kyirsta.
Lynch shot his wife numerous times in the back, head and neck while she was holding their infant daughter, according to police reports.
The bullets passed through her body, killing both mother and child, according to police reports. Lynch then turned the gun on himself in an apparent suicide attempt, but survived.
The bodies of his wife and baby remained in the family's Anchorage apartment for a weekend before they were discovered.
Lynch was found in critical condition but recovered.
At the two-day sentencing hearing at a state superior court, Lynch's public defender said the former soldier had served valiantly in combat but struggled with post traumatic stress upon returning home.
Lynch was stationed at Joint Base Elmendorf-Richardson in Anchorage at the time of the incident, which occurred just two months after he returned from a year-long deployment to Afghanistan.
Judge Michael Spaan, who imposed the sentence, concluded that Lynch's combat experience affected the former military policeman's actions.
"I believe that Mr. Lynch's service in Afghanistan was a factor," Spaan said.
But Spaan said it was unclear whether the shooting was a direct result of war-related mental problems.
"I don't even know if you had post traumatic stress, if you're still suffering from it, and what impact this might have in 20 years. The science is not exact enough to answer these questions," the judge told Lynch at sentencing.
The mother of Racquell Lynch testified by telephone at the hearing, asking for a harsh sentence.
"I accept full responsibility for what happened to my wife and daughter," Lynch said in court, reading from a statement of apology. "They will forever be in my heart."
The maximum penalty that could have been imposed on Lynch was 198 years, 99 years for each murder, under Alaska law.
(Editing by Mary Slosson and Peter Bohan)
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Friday, January 20, 2012
Obama seeks share of spotlight in Florida (AP)
WASHINGTON ? President Barack Obama is pitching a plan for boosting U.S. tourism near Orlando, just as Republican presidential candidates prepare to blanket Florida with an anti-Obama message ahead of the state's Jan. 31 primary.
Thursday's trip is the latest attempt by the White House and Obama campaign to steal a share of the spotlight from Republicans in the midst of their nomination fight. Obama held a live video conference with Iowa voters during the Republican caucus, Vice President Joe Biden held a similar event with voters in New Hampshire as primary votes there were being counted, and next week Obama will travel to Nevada, which follows Florida on the primary calendar.
Obama's high-profile trip to Florida ? the president will speak at Walt Disney World ? could help him counter attacks on his record lobbed by Republican presidential candidates during stops across the state, and in television ads already running in Florida. And it allows Obama to lay the groundwork for the general election campaign in Florida, a key political battleground he carried in 2008.
The White House said Obama would unveil a new strategy to boost tourism and travel during his speech at Disney. The announcement is part of the president's "We Can't Wait" initiative aimed at promoting executive actions Obama can take without congressional approval.
Tourism is a key component of the economy in Florida, which is burdened by 10 percent unemployment and rampant home foreclosures.
Republican front-runner Mitt Romney already has been testing economic attacks on Obama in Florida. A campaign mailer sent recently to Florida Republicans said: "Our economy has fallen flat. Who's to blame?" Another proclaims that Romney is the strongest to lead the country out of economic turmoil, arguing, "With conservative leadership, America can be first in the world in job creation again."
A recent Quinnipiac University poll showed the president in a near-statistical tie with Romney in a head-to-head matchup.
The White House insists the president's trip to Florida is not purely political. Obama spokesman Jay Carney said that if the White House couldn't travel to any state with a primary, "that would make it impossible for us."
From Florida, Obama will fly to New York City for four glitzy campaign fundraisers, including an event at the famed Apollo Theater featuring performances by Al Green and India Arie. Tickets to that fundraiser start at $100.
The president also will attend a $35,800 per ticket fundraiser at the home of director Spike Lee, and two small fundraisers at Daniel, an exclusive Manhattan restaurant. Tickets start at $5,000 for the first restaurant fundraiser and $15,000 for the second.
___
Follow Julie Pace at http://twitter.com/jpaceDC
Source: http://us.rd.yahoo.com/dailynews/rss/us/*http%3A//news.yahoo.com/s/ap/20120119/ap_on_el_pr/us_obama
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Thursday, January 19, 2012
Atlantic Tries A Business Site Again; WSJ's Delaney Will Lead ...
Nearly two years after Atlantic Media Company suspended plans for a business site, the company is back at it with nothing less that what Justin Smith calls ?our most important new launch since The Atlantic Monthly in 1857.? This version, planned for later this year, will focus on global business with Kevin Delaney as editor-in-chief.
Delaney, a star at the Wall Street Journal, left as managing editor of The Wall Street Journal (NSDQ: NWS) Online to lead the new venture, which will be based in New York rather than Atlantic?s Washington DC headquarters.
The premise/promise: a ?digital-first brand??to ?provide high-quality content and services to business executives navigating the increasingly complex global economy.? Offices are planned in Asia and Europe. (The announcement, posted below, comes just ahead of the World Economic Forum in Davos.)
The last time Atlantic went in this direction, the effort was headed by Slate founder Michael Kinsley, who is a brilliant editor but lacked a business background. The launch was delayed multiple times before Kinsley left and Atlantic finally admitted in mid-2010 that it was suspending efforts.
SEE ALSO: The Atlantic Now Gets 'More Than Half' Of Its Ad Revenues From Digital
Atlantic Media was formed by David Bradley in 1999 after the National Journal Group owner acquired the venerable Atlantic. The magazine?s digital expansion and financial turnaround under Bradley and Smith has attracted considerable attention.
They?ve been searching for ways to expand. This is a potentially lucrative area and tackling it without the costs of print attached could pay off; the lack of print doesn?t make it an inexpensive start-up proposition, though.
I?m not sure I see a stunning need for another business leadership publication but I look forward to being proven wrong.
Posted In: Companies, News Corp., Dow Jones, Wall Street Journal, Countries, Europe, Asia, atlantic media group, justin smith, kevin delaney
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